Place chicken breasts in the bottom of a slow cooker.
In a small bowl, whisk together hot sauce, chicken broth, garlic powder, onion powder, cayenne pepper, and Worcestershire sauce.
Pour the sauce mixture over the chicken.
Cover and cook on low for 4–5 hours or on high for 2–3 hours, until the chicken is tender and fully cooked.
Remove the chicken and shred with two forks.
Return the shredded chicken to the slow cooker and stir in butter.
Let it cook on low for an additional 10–15 minutes.
Serve on sandwiches, in wraps, salads, or bowls.